Infectious Diseases
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Paton AW, Chen AY, Wang H, McAllister LJ, Höggerl F, Mayr UB, Shewell LK, Jennings MP, Morona R, Lubitz W, Paton JC. 2015. Protection against Shiga-Toxigenic Escherichia coli by Non-Genetically Modified Organism Receptor Mimic Bacterial Ghosts. nfect Immun. 2015 Sep;83(9):3526-33.
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Vilte DA, Larzábal M, Mayr UB, Garbaccio S, Gammella M, Rabinovitz BC, Delgado F, Meikle V, Cantet RJ, Lubitz P, Lubitz W, Cataldi A, Mercado EC. A systemic vaccine based on Escherichia coli O157:H7 bacterial ghosts (BGs) reduces the excretion of E. coli O157:H7 in calves. Vet Immunol Immunopathol. 2012 Mar 10
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Muhammad, A., Champeimont, J., Mayr, U.B., Lubitz, W., Kudela, P. Bacterial ghosts as carriers of protein subunit and DNA-encoded antigens for vaccine applications. Expert Rev Vaccines, 11(1):97-116, 2012.
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Mayr, U.B., Kudela, P., Atrasheuskaya, A., Bukin, E., Ignatyev, G., Lubitz, W. Rectal single dose immunization of mice with Escherichia coli O157:H7 bacterial ghosts induces efficient humoral and cellular immune responses and protects against the lethal heterologous challenge. Microb Biotechnol, 5(2):283-294, 2012.
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Guan L., W. Mu, J. Champeimont, Q. Wang, H. Wu, j. Xiao, W. Lubitz, Y. Zhang, Q. Liu. 2011. Iron-regulated lysis of recombinant Escherichia coli in host to release protective antigen and confer biological containment. Infect Immun 79:2608-2618
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Riedmann E.M., W. Lubitz, J. McGrath, J.M. Kyd, A.W. Cripps. 2011. Effectiveness of engineering the nontypeable Haemophilus influenzae antigen Omp26 as an S-layer fusion in bacterial ghosts as a mucosal vaccine delivery. Human Vaccines 7: Supplement, 99-107
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Cui X., J.A. Duckworth, P. Lubitz, F.C. Molinia, C. Haller, W. Lubitz, P.E. Cowan. 2010. Humoral immune responses in brushtail possums (Trichosurus vulpecula) induced by bacterial ghosts expressing possum zona pellucida 3 protein. Vaccine 28:4268-4274
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Kudela, P., Koller, V.J., Mayr, U.B., Nepp, J., Lubitz, W., Barisani-Asenbauer, T. Bacterial Ghosts as antigen and drug delivery system for ocular surface diseases: Effective internalization of Bacterial Ghosts by human conjunctival epithelial cells. J Biotechnol, 153(3-4):167–175, 2011.
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Abtin, A., Kudela, P., Mayr, U.B., Koller, V.J., Mildner, M., Tschachler, E., Lubitz, W.: Escherichia coli ghosts promote innate immune responses in human keratinocytes. Biochem Biophys Res Commun, 400(1):78-82, 2010.
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Mayr, U. B., V. J. Koller, P. Lubitz and W. Lubitz, Bacterial ghosts as vaccine and drug delivery platforms, in Patho-Biotechnology, R. Sleator and C. Hill, Editors. 2009, Landes Bioscience: Austin, Texas, USA. p. 50-59.
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Lubitz P., U.B. Mayr, W. Lubitz. 2009. Applications of bacterial ghosts in biomedicine. Adv. Exp. Med. Biol. 655:159-70.
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Sadeghizadeh, M., Ranjbar, B., Damaghi, M., Khaki, L., Sarbolouki, M.N., Najafi, F., Parsaee, S., Ziaee, A., Massumi, M., Lubitz, W., Kudela, P., Paukner, S., Karami, A.: Dendrosomes as novel gene porters-III. J Chem Technol Biot, 83(6):912-920, 2008.
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Eko F.O., T. Barisani-Asenbauer , W Lubitz. 2008. Development of a Chlamydia trachomatis bacterial ghost vaccine to fight human blindness. Hum Vaccin. 4(3):173 - 252
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Riedmann, E., J.M. Kyd, A. W. Cripps, W. Lubitz. 2007. Bacterial ghosts as adjuvant particles. Expert Rev. Vaccines 6: 241-253.
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Ifere, G.O., Q.He, J.U Igietseme., G.A. Ananaba, D. Lyn, W. Lubitz, K.L. Kellar, C.M. Black, F.O.Eko. 2007. Immunogenicity and protection against genital Chlamydia infection and its complications by a multisubunit candidate vaccine. J. Microbiol. Immunol. Infect. 40(3):188-200
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Paukner S., T. Stiedl, P. Kudela, J. Bizik, F. Al Laham, W. Lubitz. 2006. Bacterial ghosts as a novel advanced targeting system for drug and DNA delivery. Expert Opin. Drug Deliv. 3:11-22.
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Mayr, U.B., C. Haller, W. Haidinger, A. Atrasheuskaya, E. Bukin, W. Lubitz, G. Ignatiev. 2005.Bacterial Ghosts as an Oral Vaccine: a Single Dose of Escherichia coli O157:H7 Bacterial Ghosts Protects Mice against Lethal Challenge. Inf. Immun. 73:4810-4817.
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Mayr, U.B., P. Walcher, C. Azimpour, E. Riedmann, C. Haller, W. Lubitz. 2005. Bacterial ghosts as delivery vehicles for vaccination against target antigens. Adv. Drug Delivery Rev, 57:1381-1391.
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Paukner, S., P. Kudela, G. Kohl, T. Schlapp, S. Friedrichs, W. Lubitz. 2005. DNA-loaded bacterial ghosts efficiently mediate reporter gene transfer and expression in macrophages. Molecular Therapy, 11:215-223.
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Mayrhofer, P., C. Azimpour Tabrizi, P. Walcher, W. Haidinger, W. Jechlinger, W. Lubitz. 2005. Immobilization of plasmid DNA in bacterial ghosts. J. Controlled Release 102:725-735.
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Jechlinger, W., Azimpour Tabrizi, C., Lubitz, W., Mayrhofer, P. 2004. Mini-circle DNA immobilized in bacterial ghosts: in vivo production of safe non-viral DNA delivery vehicles. J. Microbiol. Biotechnol., 8:222-231.
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Walcher, P., U.B. Mayr, C. Azimpour-Tabrizi, F.O. Eko, W. Jechlinger, P. Mayrhofer, T. Alefantis, C.V. Mujer, V. DelVecchio, W. Lubitz. 2004. Antigen discovery and delivery of subunit vaccines by nonliving bacterial ghost vectors. Exp. Rev. Vaccines 3:681-691.
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Eko, F. O., Q. He, T. Brown, L. Mcmillan, G.O. Ifere, G.A. Ananaba, D. Lyn, W. Lubitz, K.L. Kellar, C.M. Black, J.U. Igietseme. 2004. A novel recombinant multi-subunit vaccine against Chlamydia. J Immunol., 173:3375-3382.
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Azimpour Tabrizi, C., P. Walcher, U.B. Mayr, T. Stiedl, M. Binder, J. McGrath, W. Lubitz.2004. Bacterial Ghosts – Biological particles as delivery systems for antigens, nucleic acids and drugs. Current Opinion Biotech 15:530-537.
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Ebensen, T., S. Paukner, C. Link, P. Kudela, C. de Domenico, W. Lubitz, C.A. Guzmán. 2004. Bacterial ghosts are an efficient delivery system for DNA vaccines. J. Immunol. 172:6858-6865.
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Eko, F.O., W. Lubitz, L. Mcmillan, K. Ramey, T.T. Moore, G.A. Ananaba, D. Lyn, C.M. Black, J.U. Igietseme. 2003. Recombinant Vibrio cholerae ghosts as a delivery vehicle for vaccinating against Chlamydia trachomatis. Vaccine 21:1694-1703.
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Panthel, K., W. Jechlinger, A. Matis, M. Rohde, M. Szostak, W. Lubitz, R. Haas. 2003. Generation of Helicobacter pylori Ghosts by PhiX Protein E-Mediated Inactivation and Their Evaluation as Vaccine Candidates. Infect. Immunity 71:109-116.
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Jalava, K., A. Hensel, M. Szostak, S. Resch, W. Lubitz. 2002. Bacterial ghosts as vaccine candidates for veterinary applications. J. Control. Release 85:17-25.
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Jechlinger, W., Haidinger, W., Paukner, S., Mayrhofer, P., Riedman, E., Marchart, J., Mayr, U., Haller, C., Kohl, G., Walcher, P., Kudela, P., Bizik, J., Felnerova, D., Denner, E.M.B., Indra, A., Haslberger, A., Szostak, M., Resch, S., Eko, F., Schukovskaya, T., Kutyrev, V., Hensel, A., Friederisch, S., Schlapp, T., Lubitz, W.: Bacterial ghosts as carrier and targeting systems for antigen delivery. In: Vaccine Delivery Strategies, Dietrich G. and Goebel W., eds. Horizon Scientific Press, Wymondham, Norfolk, UK, pp. 163-184, 2002.
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Lubitz, W. 2001. Bacterial ghosts as carrier and targeting systems. Expert Opin. Biol. Ther. 1:765-771.
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Eko, F.O., A. Witte, V. Huter, B. Kuen, S. Fürst-Ladani, A. Haslberger, A. Katinger, A. Hensel. M.P. Szostak, S. Resch, H. Mader, P. Raza, E. Brand, J. Marchart, W. Jechlinger, W. Haidinger, W. Lubitz. 1999. New strategies for combination vaccines based on the extended recombinant bacterial ghost system. Vaccine 17: 1643-1649.
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Mader, H.J., M.P. Szostak, A. Hensel, W. Lubitz, A.G. Haslberger. 1997. Endotoxicity does not limit the use of bacterial ghosts as candidate vaccine. Vaccine 15:195-202.