Cancer Immunotherapy
-
Dobrovolskienė N, Pašukonienė V, Darinskas A, Kraśko JA4, Žilionytė K, Mlynska A, Gudlevičienė Ž, Mišeikytė-Kaubrienė E, Schijns V, Lubitz W, Kudela P, Strioga M. 2018. Tumor lysate-loaded Bacterial Ghosts as a tool for optimized production of therapeutic dendritic cell-based cancer vaccines. Vaccine. 2018 Jul 5;36(29):4171-4180. doi: 10.1016/j.vaccine.2018.06.016. Epub 2018 Jun 9.
-
Diana Groza, Sebastian Gehrig, Pavol Kudela, Martin Holcmann, Christine Pirker, Carina Dinhof, Hemma H. Schueffl, Marek Sramko, Julia Hoebart, Fatih Alioglu, Michael Grusch, Manfred Ogris, Werner Lubitz, Bernhard K. Keppler, Irena Pashkunova-Martic, Christian R. Kowol, Maria Sibilia, Walter Berger & Petra Heffeter. 2018. Bacterial ghosts as adjuvant to oxaliplatin chemotherapy in colorectal carcinomatosis. Oncoimmunology, 2018 Feb 16;7 e1424676. eCollection 2018.
-
Kraśko JA, Žilionytė K, Darinskas A, Strioga M, Rjabceva S, Zalutsky I, Derevyanko M, Kulchitsky V, Lubitz W, Kudela P, Miseikyte-Kaubriene E, Karaman O, Didenko H, Potebnya H, Chekhun V, Pašukonienė V. 2017. Bacterial ghosts as adjuvants in syngeneic tumour cell lysate-based anticancer vaccination in a murine lung carcinoma model. Oncol Rep. 2017 Jan;37(1):171-178.
-
Michalek J, Hezova R, Turanek-Knötigova P, Gabkova J, Strioga M, Lubitz W, Kudela P. 2017. Oncolysate-loaded Escherichia coli bacterial ghosts enhance the stimulatory capacity of human dendritic cells. Cancer Immunol Immunother. 2017 Feb;66(2):149-159.
-
Kudela, P., Sun, Z., Fourcade, J., Janjic, B., Kirkwood, J.M., Maillere, B., Zarour, H.M.: Epitope hierarchy of spontaneous CD4+ T cell responses to LAGE-1. J Immunol, 186(1):312-322, 2011.
-
Fourcade, J., Sun, Z.,Kudela, P., Janjic, B., Kirkwood, J.M., El-Hafnawy, T., Zarour, H.M.: Human Tumor Antigen-Specific Helper and Regulatory T Cells Share Common Epitope Specificity but Exhibit Distinct T Cell Repertoire. J Immunol, 184(12):6709-6718, 2010.
-
Kudela, P., Koller, V.J., Lubitz, W.: Bacterial Ghosts (BGs) – Advanced Antigen and Drug Delivery System. Vaccine, 28(36):5760-5767, 2010.
-
Mayr, U. B., V. J. Koller, P. Lubitz and W. Lubitz, Bacterial ghosts as vaccine and drug delivery platforms, in Patho-Biotechnology, R. Sleator and C. Hill, Editors. 2009, Landes Bioscience: Austin, Texas, USA. p. 50-59.
-
Lubitz P., U.B. Mayr, W. Lubitz. 2009. Applications of bacterial ghosts in biomedicine. Adv. Exp. Med. Biol. 655:159-70.
-
Fourcade, J., Kudela, P., Sun, Z., Shen, H., Land, S.R., Lenzner, D., Guillaume, P., Luescher, I.F., Sander, C., Ferrone, S., Kirkwood, J.M., Zarour, H.M.: PD-1 Is a Regulator of NY-ESO-1-Specific CD8+ T Cell Expansion in Melanoma Patients. J Immunol, 182(9):5240-5249, 2009.
-
Kudela P., S. Paukner, U.B. Mayr, D. Cholujova, G. Kohl G, Z. Schwarczova, J. Bizik, J. Sedlak, W. Lubitz. 2008. Effective gene transfer to melanoma cells using bacterial ghosts. Cancer Letters 262(1):54-63
-
Sadeghizadeh, M., Ranjbar, B., Damaghi, M., Khaki, L., Sarbolouki, M.N., Najafi, F., Parsaee, S., Ziaee, A., Massumi, M., Lubitz, W., Kudela, P., Paukner, S., Karami, A.: Dendrosomes as novel gene porters-III. J Chem Technol Biot, 83(6):912-920, 2008.
-
Fourcade, J., Kudela, P., Andrade Filho, P.A., Janjic, B., Land, S.R., Sander, C., Krieg, A., Donnenberg, A., Shen, H., Kirkwood, J.M., Zarour, H.M.: Immunization with analog peptide in combination with CpG and Montanide expands tumor antigen-specific CD8+ T cells in melanoma patients. J Immunother, 31(8):781-791, 2008.
-
Kudela, P., Janjic, B., Fourcade, J., Castelli, F., Andrade, P., El-Hefnawy, T., Amicosante, M., Kirkwood, J.M., Maillere, B., Zarour, H.M.: Cross-Reactive CD4+ T Cells against One Immunodominant Tumor-Derived Epitope in Melanoma Patients. J Immunol, 179(11):7932-7940, 2007.
-
Paukner S., T. Stiedl, P. Kudela, J. Bizik, F. Al Laham, W. Lubitz. 2006. Bacterial ghosts as a novel advanced targeting system for drug and DNA delivery. Expert Opin. Drug Deliv. 3:11-22.
-
Janjic, B., Andrade, P., Wang, X.F., Fourcade, J., Almunia, C., Kudela, P., Brufsky, A., Jacobs, S., Friedland, D., Stoller, R., Gillet, D., Herberman, R.B., Kirkwood, J.M., Maillere, B., Zarour, H.M.: Spontaneous CD4+ T cell response against TRAG-3 in patients with melanoma and breast cancer. J Immunol, 177(4):2717-2727, 2006.
-
Paukner, S., P. Kudela, G. Kohl, T. Schlapp, S. Friedrichs, W. Lubitz. 2005. DNA-loaded bacterial ghosts efficiently mediate reporter gene transfer and expression in macrophages. Molecular Therapy, 11:215-223.
-
Kudela, P., S. Paukner, U.B. Mayr, D. Cholujova, Z. Schwarczova, J. Sedlak, J. Bizik, W. Lubitz. 2005. Bacterial ghosts as novel efficient targeting vehicles for DNA delivery to the human monocytes-derived dendritic cell. J. Immunotherapy, 28:136-143.
-
Mayrhofer, P., C. Azimpour Tabrizi, P. Walcher, W. Haidinger, W. Jechlinger, W. Lubitz. 2005. Immobilization of plasmid DNA in bacterial ghosts. J. Controlled Release 102:725-735.
-
Jechlinger, W., Azimpour Tabrizi, C., Lubitz, W., Mayrhofer, P. 2004. Mini-circle DNA immobilized in bacterial ghosts: in vivo production of safe non-viral DNA delivery vehicles. J. Microbiol. Biotechnol., 8:222-231.
-
Azimpour Tabrizi, C., P. Walcher, U.B. Mayr, T. Stiedl, M. Binder, J. McGrath, W. Lubitz.2004. Bacterial Ghosts – Biological particles as delivery systems for antigens, nucleic acids and drugs. Current Opinion Biotech 15:530-537.
-
Paukner,S, G. Kohl, W. Lubitz. 2004. Bacterial ghosts as novel advanced drug delivery systems: antiproliferative activity of loaded doxorubicin in human Caco-2 cells. J. Control. Release 94:63-74.
-
Paukner, S., G. Kohl, K. Jalava, W. Lubitz. 2003. Sealed bacterial ghosts-novel targeting vehicles for advanced drug delivery of water-soluble substances. J. Drug Target. 11:151-161.
-
Eleveld-Trancikova, D., Kudela, P., Majerciak, V., Regendova, M., Zelnik, V., Pastorek, J., Pastorekova, S., Bizik, J.: Suppression subtractive hybridisation to isolate differentially expressed genes involved in invasiveness of melanoma cell line cultured under different conditions. Int J Oncol, 20(3):501-508, 2002.
-
Lubitz, W. 2001. Bacterial ghosts as carrier and targeting systems. Expert Opin. Biol. Ther. 1:765-771.
-
Kudela, P., Schwarczova, Z., Sedlak, J., Bizik, J.: Conditioned medium from Hela cells enhances motility of human monocyte-derived dendritic cells but abrogates their maturation and endocytic activity. Neoplasma, 48(5):382-388, 2001.
-
Bizik, J., Trancikova, D., Felnerova, D., Sedlakova, O., Kudela, P., Vaheri, A.: Invasion of human melanoma cells into dermal equivalents. In: Intramolecular cross-talk in tumor metastasis, Skouteris G., ed. NATO-ASI book series. NOMEN NESCIO IOS Press, Amsterdam, NL, 79-93, 1999.